CT-derived FFR vs. Invasive FFR for the Management of Moderate Coronary Artery Stenosis: A Case Study
Participating Physicians
Cardiology fellow, Division of Cardiovascular Medicine, Clemenceau Medical Center; Faculty of Medicine and Medical Sciences, University of Balamand
Dr. Elie Chammas, MD, FESC, FACC
Chief of the Heart Center at Clemenceau Medical Center (affiliated with Johns Hopkins International), Professor of Cardiology, and Associate Dean for Clinical Affairs, Balamand University
Assistant Professor of Cardiology, University of Balamand; Director of Non-invasive Cardiology, Clemenceau Medical Center (Affiliated with John Hopkins International)
Case Summary
A 69-year-old woman presented with acute chest pain.
- CCTA Findings: Mid-LAD intermediate stenosis (50–69%)
- DVFFR Findings: 0.83 (borderline ischemic)
- Invasive FFR Findings: 0.81 (borderline ischemic)
The close match between DVFFR and invasive FFR confirmed the lesion’s minimal functional impact, leading to medical management without stenting. Both modalities ruled out ischemia in other vessels (LCX and RCA), underscoring DVFFR’s value in identifying functionally insignificant lesions.
DVFFR analysis demonstrating blood flow measurements in the coronary arteries, matching invasive FFR results.
Clinical Significance
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